Risk of Breast Cancer a big question. Young women with high body fat have a lower chance of developing premenopausal breast cancer, according to scientists at the National Institutes of Health and collaborators. These findings may help researchers better understand the role obesity plays in breast cancer risk.
“Women who are high in fat, especially after menopause, are known to carry an increased risk of postmenopausal breast cancer,” said Dr. Dale Sandler, senior co-author and head of the epidemiology branch at the National Institute of the Environment.
It does not increase in obese women before menopause, but in fact, shrinks. This suggests that different biological mechanisms are responsible for causing breast cancer in younger women.
Highlight risk of Breast Cancer factors:
She said breast cancer appeared relatively rare before menopause, and the researchers found it difficult to fully assess risk factors in one study. Previous studies suggest that risk factors for BC in younger women may not be the same in older women.
To understand the risk of breast cancer in premenopausal women
en, Sandler and other researchers formed a group from which data were collected from 19 different studies, involving 758,592 women from around the world. This approach allowed the team to identify risk factors and patterns that are difficult to detect with fewer women.
The number of participants in the studies ranged from 18 to 54 at the beginning of the study. For each individual study, volunteers filled several rounds of questionnaires, which included height, weight and other health-related factors.
From this information, the researchers assessed the risk of breast cancer in relation to body mass index (BMI) in the following age groups: 18-24, 25-34, 35-44, 45-54.
Ratios and numbers
The scientists found that the relative risk of premenopausal breast cancer fell by 12 to 23 percent for each five-unit BMI increase by age.
The strongest BMI effect was observed at ages 18 to 24, with very obese women in this age group 4.2 times less likely to have premenopausal breast cancer than women with low BMI at the same age.
While Sandler and her colleagues are not sure why they protect them from BC, she warns that young women should not deliberately gain weight to reduce their risk of breast cancer.
“We hope this will be the first of many studies to focus specifically on breast cancer factors among young women,” she concluded.